Reduce drying time and improve uniformity with controlled fluidization

The Gansons Fluidised Bed Dryer is designed to dry powders and granules by suspending particles in a controlled stream of heated air, ensuring uniform contact between air and material. This fluidization enables consistent moisture removal across the entire batch while maintaining product integrity.

The system features a proprietary Cyklon air distribution design that generates a controlled swirl-flow pattern inside the process chamber. This eliminates dead zones and prevents material stagnation, significantly improving drying efficiency while reducing particle attrition and product loss.

The airflow system allows precise control over drying parameters, supported by push-pull fan configuration for stable and reproducible process conditions. This results in shorter drying times and consistent batch outcomes, even for sensitive or high-value materials.

The equipment is designed for pharmaceutical production environments, with cGMP-compliant construction, wash-in-place systems, and options for high-containment processing. Automation systems support recipe control, data integrity, and integration into regulated production workflows.

The system is scalable from development to production, with capacities ranging from approximately 10 L to 1,500 L.

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Achieve rapid and uniform wet granulation with controlled mixing and shear

The Gansons High Shear Mixer Granulator is designed for fast and controlled wet granulation of pharmaceutical powders, combining high-intensity mixing with precise binder distribution and granule formation. The system enables solid-solid and solid-liquid processing within a single vessel, producing dense and uniform granules for tablet formulation.

The process is driven by a proprietary impeller and chopper configuration that creates strong vortex movement and efficient powder recirculation. This ensures homogeneous mixing across varying bulk densities while promoting rapid granule growth and consistent particle size distribution.

The chopper supports both binder distribution and deagglomeration, preventing oversized agglomerates and improving granule uniformity. The optimized process bowl geometry eliminates dead zones and enhances material flow into the shear zone, ensuring repeatable processing results.

Integrated automation monitors parameters such as torque, power, and time to enable accurate end-point detection and reproducible batch performance. The system supports recipe-driven operation and complies with regulatory requirements for data integrity and process control.

The equipment is designed for safe pharmaceutical production with features such as wash-in-place cleaning, sealed shaft systems to prevent contamination, and optional ATEX-compliant designs. Available in capacities ranging from laboratory to large-scale production, the system supports scalable process development and manufacturing.

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Achieve uniform and reproducible tablet coating at scale

The Gansons GansCoater is a high-performance tablet coating system designed for pharmaceutical production environments requiring consistent coating quality and regulatory compliance. The system supports a wide range of coating applications including film coating, enteric coating, multi-layer functional coating, and sugar coating.

The coating process is optimized through a combination of proprietary spray nozzles, controlled air handling, and engineered mixing dynamics inside the coating pan. The GHPN spray nozzles generate uniform droplet size with wide coverage, reducing spray losses and compressed air consumption while maintaining consistent coating distribution.

The coating drum is designed with a highly polished surface and optimized perforation geometry to improve drying efficiency and reduce tablet abrasion. Aeroflo baffles enhance tablet movement and airflow interaction, eliminating dead zones and improving mixing performance and coating uniformity.

The system supports fast changeovers through interchangeable coating pans and automated loading and unloading. Integrated process control with PLC or SCADA systems ensures reproducible operation, recipe management, and compliance with regulatory standards such as 21 CFR Part 11.

The GansCoater is available across a wide capacity range from laboratory to large-scale production, with batch sizes ranging from approximately 500 g up to 1,000 kg.

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Fills and Seals Capsules with Precision

The GKF 702 from Syntegon offers a versatile solution tailored for R&D labs and small batch production, capable of handling up to 42,000 capsules per hour. This capsule filling machine excels in precise dosing of both HPMC and gelatin capsules with a modular design that facilitates quick changeovers between different product types, including powders, granules, and liquids. Utilizing a slide-gate technology, it ensures minimal product loss and maximized yields. Integrated with automated systems for dosing and weighing, it optimizes productivity in pharmaceutical, nutraceutical, and health product manufacturing. The machine’s design supports seamless integration into production lines with minimal operational downtime. With robust material options and compliance with industry standards, the GKF 702 ensures reliability and efficiency in diverse processing environments.

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Fills and Seals Capsules with Precision

The GKF Capsylon Series from Syntegon is an automated solution for precise capsule filling and sealing, tailored for the nutraceutical and pharmaceutical sectors. With a modular design, these machines adapt to fill a range of capsule types, from powders to granules, effectively reducing product waste and improving yield. Capable of producing up to 360,000 capsules per hour, the series is ideal for high-volume operations, including vitamins, probiotics, and herbal supplements. Integration into existing production lines is seamless, thanks to its PLC control and user-friendly interface. The machines are energy-efficient, featuring slide-gate technology that minimizes dust and product loss. Built from robust materials, they are compliant with GMP standards, ensuring quality and safety. Maintenance is streamlined through easy-to-clean components and optional CIP systems, while Syntegon offers extensive customization and support to meet diverse production needs.

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Detects Particulate and Cosmetic Defects

The AIM 8000 series from Syntegon represents cutting-edge technology in automated visual inspection systems. These machines specialize in the detection of particulate and cosmetic defects in pharmaceutical products, such as ampoules, vials, syringes, and cartridges. Using high-resolution camera systems and AI-driven image analysis, the AIM 8000 series enhances inspection accuracy while minimizing false rejects.

With its modular design, the AIM 8000 series accommodates a variety of container sizes and formats, ranging from 1 ml to larger capacities, ensuring flexibility in handling different products like insulin vials, vaccines, and biologics in cartridges. The system offers a throughput of up to 600 containers per minute, integrating seamlessly into both continuous and batch production lines.

Designed for efficiency, these machines utilize intelligent pre-spinning functions to homogenize products and eliminate air bubbles, further optimizing the inspection process. The incorporation of PLC control facilitates seamless automation and integration with existing line setups, while maintaining energy efficiency with its optimized motor systems.

Constructed from high-grade stainless steel, the AIM 8000 series ensures durability and resistance to corrosion, meeting stringent GMP and FDA compliance standards essential for pharmaceutical applications. Additionally, it features a built-in re-inspection function and supports Container Closure Integrity (CCI) testing, solidifying its role as a critical component in maintaining product safety and quality.

Engineered for ease of use, the series supports quick changeovers and includes customizable features to meet specific production needs, backed by Syntegon’s engineering support for tailored solutions.

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Fills, Seals, and Packs Diverse Products

The VFFS Packaging Machine from Syntegon revolutionizes packaging with its versatile design for both the food and pharmaceutical industries. It excels in filling, sealing, and packing various products such as bread rolls, cornflakes, and espresso pods. Utilizing continuous and high-speed operation, it seamlessly integrates into existing production lines, enhancing efficiency. The machine supports multiple bag styles, including Doy Zip and stick packs, and boasts an easy-to-use HMI for rapid changeovers and minimal downtime. Built with robust servo technology, it ensures energy efficiency and precision, helping manufacturers meet stringent hygiene and industry standards. Custom engineering options and maintenance services are available to match specific operational needs.

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Automates Product Handling and Packaging Processes

The Syntegon Robotic Pick and Place Platform (RPP) offers a game-changing solution for diverse industries seeking to advance their packaging operations. This modular platform excels in automating product handling and placement with precision and efficiency.

Using integrated delta robots, the RPP system provides seamless product loading into trays or cartons, capable of achieving up to 140 picks per minute per robot, optimizing high-speed environments. Its design supports applications across pharmaceuticals, bakery products, confectionery, dairy, and more, enhancing operations from ampoules to chocolate bars.

With its compact footprint, the RPP is PLC-controlled, supporting remote monitoring and smart interface integration for scalable capacity adjustments. Its construction in stainless steel offers superior hygienic operations and compliance with rigorous industry standards, including IP65 protection for wash-down scenarios. The platform’s vision-guided inspection technologies ensure tight quality control, identifying and removing any defective products in the process.

Syntegon’s RPP system includes quick-change end-of-arm tooling for format flexibility, supporting gentle and safe product handling while reducing contamination risks. It simplifies cleaning with its open-channel, self-draining design, paired with optional CIP systems. Custom configurations and engineering support are available to tailor the platform to your specific production demands, ensuring streamlined integration into existing production lines.

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Processes and Coats Pharmaceutical Powders and Tablets

The comprehensive range of equipment from Syntegon, including mixers, granulators, dryers, tablet presses, tablet coaters, and capsule fillers, is designed to enhance pharmaceutical production efficiency. These machines support various processes, such as mixing, granulating, drying, and tablet pressing, crucial for creating products like paracetamol powder, ibuprofen tablets, and vitamin D capsules. Operating under batch, pilot, or continuous modes, these systems are equipped with Automated Process Development (APD) capabilities for precision and optimization. The equipment offers high throughput and adaptability, tailored for pharmaceutical manufacturers and R&D labs. Constructed with corrosion-resistant materials, it meets GMP and FDA standards. Clean-in-place (CIP) systems are integrated for efficient maintenance, while customization options include process parameters and engineering support to suit specific production needs.

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