Enables Precise Dosing and Continuous Production

The Xelum Continuous Manufacturing Platform from Syntegon is a transformative solution for the pharmaceutical and nutraceutical industries, offering seamless integration of precise dosing and continuous production for oral solid dosage forms. By leveraging discrete mass dosing, the Xelum platform eliminates the need for traditional scale-up, ensuring high content uniformity even for APIs below 1%. This system is ideal for producing a variety of products such as antibiotic tablets and antiviral capsules, thanks to its robust fluid bed processors that handle granulation and drying in a single chamber, avoiding wet granulate transfer and enhancing reliability. With throughput capacities ranging from 10 to 100 kg/h, Xelum supports rapid production cycles and maintains exact standards in API concentration.

The platform is fully automated, featuring PLC-controlled operations with direct process parameter transfers from R&D to production, allowing for efficient pilot and clinical trials without the constraints of scaling up. It accommodates complex formulations with contained capabilities for OEB4 materials and integrated WIP systems. Xelum’s design prioritizes energy efficiency, reducing production costs while maintaining flexibility for both tablets and capsules. Engineered to meet stringent GMP and FDA standards, it offers a clean-in-place (CIP) system ensuring fast, contamination-free cleaning, perfect for high-potent API development. Customization support allows for tailored configurations to suit specific manufacturing requirements, making Xelum a cornerstone for forward-looking production strategies.

The post Ciągłe wytwarzanie produktów farmaceutycznych appeared first on Vekamaf.com Poland.

Fills and Seals Capsules with Precision

The GKF 702 from Syntegon offers a versatile solution tailored for R&D labs and small batch production, capable of handling up to 42,000 capsules per hour. This capsule filling machine excels in precise dosing of both HPMC and gelatin capsules with a modular design that facilitates quick changeovers between different product types, including powders, granules, and liquids. Utilizing a slide-gate technology, it ensures minimal product loss and maximized yields. Integrated with automated systems for dosing and weighing, it optimizes productivity in pharmaceutical, nutraceutical, and health product manufacturing. The machine’s design supports seamless integration into production lines with minimal operational downtime. With robust material options and compliance with industry standards, the GKF 702 ensures reliability and efficiency in diverse processing environments.

The post Napełnianie kapsułek dla farmaceutyków i nutraceutyków appeared first on Vekamaf.com Poland.

Fills and Seals Capsules with Precision

The GKF Capsylon Series from Syntegon is an automated solution for precise capsule filling and sealing, tailored for the nutraceutical and pharmaceutical sectors. With a modular design, these machines adapt to fill a range of capsule types, from powders to granules, effectively reducing product waste and improving yield. Capable of producing up to 360,000 capsules per hour, the series is ideal for high-volume operations, including vitamins, probiotics, and herbal supplements. Integration into existing production lines is seamless, thanks to its PLC control and user-friendly interface. The machines are energy-efficient, featuring slide-gate technology that minimizes dust and product loss. Built from robust materials, they are compliant with GMP standards, ensuring quality and safety. Maintenance is streamlined through easy-to-clean components and optional CIP systems, while Syntegon offers extensive customization and support to meet diverse production needs.

The post Napełnianie kapsułek dla produktów żywieniowych i zdrowotnych appeared first on Vekamaf.com Poland.

Ensures Precise Capsule Weighing and Quality Control

The KKE series from Syntegon offers a range of capsule checkweighers designed for pharmaceutical and nutraceutical production lines, ensuring precise weight control and quality assurance. Utilizing patented gravimetric weighing technology, these checkweighers deliver 100% capsule weighing accuracy, making them essential for applications involving gelatin, vegetarian, and specialty capsules such as probiotic and Omega-3 variants. Models like the KKE 1700 and KKE 3800 cater to medium and large volume productions, with throughputs ranging from 103,200 to 232,200 capsules per hour. Integrated with automated feedback loops and ASB (Automated Troubleshooting) functions, these machines enhance process efficiency and reduce downtime. Constructed to meet OEB 4 and OEB 5 standards, they offer dust-tight and wet-clean options for stringent compliance. The series is engineered for seamless in-line integration with Syntegon’s GKF capsule filling machines and provides robust support for CIP, ensuring easy maintenance and cleaning. With configurable options and engineering support, the KKE series is designed to optimize your production line while maintaining industry compliance and product quality.

The post System ważenia kontrolnego kapsułek do produkcji farmaceutycznej appeared first on Vekamaf.com Poland.

Fills and Seals Vials for Liquid Pharmaceuticals

The FLC 3000 from Syntegon is designed to efficiently fill and seal vials in liquid pharmaceutical production lines, particularly for high-demand products like Covid-19 vaccines and monoclonal antibodies. Its compact GMP-compliant design supports a wide filling range of 0.2 to 500 milliliters and achieves throughput of up to 600 vials per minute, reducing changeover times with only three format part sets required. The machine’s peristaltic pump technology ensures precise dosing while maintaining sterility, and it integrates seamlessly into production environments with options for full in-process control. A clean and hygienic design facilitates easy maintenance and operator safety, meeting stringent GMP and FDA requirements. The FLC 3000 can be customized with additional filling technologies and systems as needed, providing robust support for both batch and continuous operations.

The post System napełniania cieczą fiolek luzem appeared first on Vekamaf.com Poland.

Detects Particulate and Cosmetic Defects

The AIM 8000 series from Syntegon represents cutting-edge technology in automated visual inspection systems. These machines specialize in the detection of particulate and cosmetic defects in pharmaceutical products, such as ampoules, vials, syringes, and cartridges. Using high-resolution camera systems and AI-driven image analysis, the AIM 8000 series enhances inspection accuracy while minimizing false rejects.

With its modular design, the AIM 8000 series accommodates a variety of container sizes and formats, ranging from 1 ml to larger capacities, ensuring flexibility in handling different products like insulin vials, vaccines, and biologics in cartridges. The system offers a throughput of up to 600 containers per minute, integrating seamlessly into both continuous and batch production lines.

Designed for efficiency, these machines utilize intelligent pre-spinning functions to homogenize products and eliminate air bubbles, further optimizing the inspection process. The incorporation of PLC control facilitates seamless automation and integration with existing line setups, while maintaining energy efficiency with its optimized motor systems.

Constructed from high-grade stainless steel, the AIM 8000 series ensures durability and resistance to corrosion, meeting stringent GMP and FDA compliance standards essential for pharmaceutical applications. Additionally, it features a built-in re-inspection function and supports Container Closure Integrity (CCI) testing, solidifying its role as a critical component in maintaining product safety and quality.

Engineered for ease of use, the series supports quick changeovers and includes customizable features to meet specific production needs, backed by Syntegon’s engineering support for tailored solutions.

The post Zautomatyzowana kontrola wizualna produktów farmaceutycznych appeared first on Vekamaf.com Poland.

Fills and Packages Nutraceutical Capsules and Granules

Syntegon’s Nutraceutical Granule and Capsule Filling System offers a comprehensive solution tailored for the needs of nutraceutical producers and pharmaceutical manufacturers. Designed to improve operational efficiency, this system precisely fills capsules and packages granules, ensuring accurate dosage and minimal waste. Integrating seamlessly into both batch and continuous operations, it supports various production scales. The system accommodates a wide array of applications from encapsulating omega-3 capsules and vitamin tablets to packaging protein powder sachets and probiotic gummies.

With automation at its core, the system is equipped with PLC controls for streamlined operations and offers remote monitoring for enhanced production oversight. The equipment is constructed with durable stainless steel options, ensuring compliance with GMP standards and reliability under extensive operational use. Maintenance is efficient with an integrated CIP system that allows thorough cleaning without manual intervention. Additionally, customization options are available to adapt filling and packaging capabilities to specific product requirements, providing engineering support to optimize your production line.

The post Przetwarzanie i pakowanie produktów nutraceutycznych appeared first on Vekamaf.com Poland.

Assembles, Labels, and Packages Medical Devices

The Range Device Assembly (RMA) system from Syntegon is a versatile solution for assembling, labeling, and packaging specialized medical devices such as insulin pens, IV catheters, and prefilled syringes. This system excels in flexibility, accommodating both small batch clinical trials and high-speed production lines. It employs modular assembly machines capable of handling complex tasks, from precise component assembly to accurate labeling and efficient packaging. The system supports semi-automatic and fully-automatic operations, integrating seamlessly with upstream and downstream processes, including filling and sealing. With a processing capacity of up to 200 devices per minute, it offers high throughput while maintaining stringent cleanability and control standards. Designed with easy maintenance and CIP capabilities, it complies with GMP standards, making it ideally suited for pharmaceutical and MedTech applications. Its modular design ensures customization options to meet specific production requirements, with engineering support available for tailored solutions.

The post Rozwiązania montażowe dla urządzeń medycznych appeared first on Vekamaf.com Poland.

Forms, Fills, and Seals with Paper Materials

The TPU Forming, Filling, and Sealing Machine from Syntegon offers a transformative approach to sustainable packaging through its innovative use of paper materials. This machine reduces plastic dependency by molding paper into 3D shapes, ideal for various sectors, including food, cosmetics, and electronics. It efficiently processes diverse end-products like chocolate bars, vitamin blister packs, and toothpaste tubes, meeting modern sustainability demands.

With a modular design, the TPU adapts to production needs ranging from small batches to medium-sized runs, ensuring seamless integration into existing production lines. It supports continuous and scalable operations, offering automation through its PLC-controlled systems, which allow for remote monitoring and adjustments.

The machine operates using a precise forming, filling, and sealing process, ensuring optimal product protection with or without barrier layers. The compact and energy-efficient design is engineered to meet environmental and operational objectives, using significantly less plastic than traditional means.

Manufacturers benefit from customization options, such as adaptable forming mechanics to suit specific packaging requirements and engineering support for tailored implementations. The TPU also complies with stringent industry standards, enhancing its appeal for forward-thinking companies aiming to enhance their sustainable packaging initiatives.

The post Technologia formowania papieru dla zrównoważonych opakowań appeared first on Vekamaf.com Poland.

Processes and Coats Pharmaceutical Powders and Tablets

The comprehensive range of equipment from Syntegon, including mixers, granulators, dryers, tablet presses, tablet coaters, and capsule fillers, is designed to enhance pharmaceutical production efficiency. These machines support various processes, such as mixing, granulating, drying, and tablet pressing, crucial for creating products like paracetamol powder, ibuprofen tablets, and vitamin D capsules. Operating under batch, pilot, or continuous modes, these systems are equipped with Automated Process Development (APD) capabilities for precision and optimization. The equipment offers high throughput and adaptability, tailored for pharmaceutical manufacturers and R&D labs. Constructed with corrosion-resistant materials, it meets GMP and FDA standards. Clean-in-place (CIP) systems are integrated for efficient maintenance, while customization options include process parameters and engineering support to suit specific production needs.

The post Sprzęt badawczo-rozwojowy dla farmaceutycznych stałych postaci dawkowania appeared first on Vekamaf.com Poland.